Body

Why are we sometimes full?

In the hypothalamus, the basal core deep in the brain, you will find a hunger center and a satiety center. Extra activity in these centers makes us feel full or hungry. If food enters the stomach bag and sets it up, the production of hunger hormone ghrelin is inhibited. That gives a full feeling. When nutrients from food are passed through the liver through the blood, the glucose concentration in the blood is recorded. This is reported to the hypothalamus via autonomic nerve pathways, which contributes to the feeling of satiety. The concentration of amino acids and fats also influences the hypothalamus and gives a full feeling. The hormone leptin is found in fat cells and is released when the fat in the cells increases. An increased concentration of leptin in the blood also gives a feeling of satiety and helps regulate energy conversion. If people have a mutation in the leptin gene, they have difficulty regulating their food intake. After all, they never feel completely full - and eventually get too fat.

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